What is Bicuspid Valve? A Simplified Guide

Heart disease is one of the leading causes of death worldwide, and one of the most common heart conditions is a bicuspid aortic valve. If you or someone you know has been diagnosed with a bicuspid valve, it’s important to understand what it is, how it can affect your health, and what your treatment options are. In this article, we’ll simplify the topic and help you understand everything you need to know about bicuspid valves.

What is a Bicuspid Valve?

The human heart has four valves that help regulate blood flow through the heart and body: the aortic valve, mitral valve, tricuspid valve, and pulmonary valve. The aortic valve is located between the heart and the aorta, which is the main artery that carries oxygen-rich blood from the heart to the rest of the body. Normally, the aortic valve has three leaflets or flaps that open and close to allow blood to flow through.

A bicuspid aortic valve is a heart condition where the aortic valve only has two leaflets or flaps instead of three. This means that the valve may not function as well and there may be reduced blood flow through the heart and body. Bicuspid valves are the most common congenital heart defect, affecting 1-2% of the population. It is also seen more often in males than in females.

Causes of Bicuspid Valves:

  • Genetics: Bicuspid aortic valves are thought to be caused by genetic mutations or abnormalities. This means that if someone in your family has a bicuspid valve, you may be more likely to have one as well.
  • Fetal Development: Bicuspid aortic valves can also develop during fetal development. The exact cause is unknown, but there may be an association with abnormal blood flow during the early stages of pregnancy.

Diagnosing Bicuspid Valves:

Many people with bicuspid aortic valves don’t experience any symptoms and the condition is only discovered during routine medical exams or tests for other conditions. However, when symptoms do occur, they can include:

  • Shortness of breath
  • Chest pain or tightness
  • Heart palpitations
  • Fainting or lightheadedness
  • Difficulty exercising or doing physical activities

To diagnose a bicuspid valve, your doctor may recommend:

  • Echocardiogram: This is a non-invasive test that uses sound waves to create images of the heart. It’s the most common test used to diagnose a bicuspid valve.
  • Cardiac MRI: A magnetic resonance imaging (MRI) scan of the heart can provide more detailed images of the valve and surrounding structures.
  • CT scan: A computed tomography (CT) scan can also provide detailed images of the heart and valve.

Complications Associated with Bicuspid Valves:

While many people with bicuspid aortic valves live normal, healthy lives, the condition can sometimes lead to complications that require medical treatment or surgery:

Aortic Stenosis:

Aortic stenosis is a common complication of bicuspid aortic valves. It occurs when the valve becomes narrowed or tight, which can reduce blood flow through the heart and increase the workload on the heart. Symptoms of aortic stenosis include chest pain, difficulty breathing, and fainting. Severe cases of aortic stenosis may require surgery to replace the valve.

Aortic Regurgitation:

Aortic regurgitation occurs when the valve doesn’t close completely, which allows blood to leak back into the heart. This can cause symptoms such as shortness of breath, chest pain, and fatigue. In severe cases, the condition may require surgery to repair or replace the valve.


Endocarditis is an infection of the heart’s inner lining (endocardium) that can occur when bacteria enter the bloodstream and attach to damaged heart valves. People with bicuspid aortic valves may be at increased risk of developing endocarditis, and the condition can be life-threatening if left untreated. Symptoms can include fever, fatigue, joint pain, and shortness of breath. Treatment typically involves antibiotics and hospitalization.

Treatment for Bicuspid Valves:

Treatment for a bicuspid valve will depend on the severity of the condition, the presence of complications, and the patient’s overall health. If a bicuspid valve is discovered during routine testing and the patient isn’t experiencing any symptoms, the doctor may simply monitor the valve through regular check-ups and tests.

If complications arise or symptoms develop, treatment options may include:

  • Medications: Drugs such as beta blockers, calcium channel blockers, or ACE inhibitors can help manage symptoms of aortic stenosis or aortic regurgitation.
  • Surgery: If the valve is severely damaged or the patient experiences life-threatening complications, surgery may be required to replace or repair the valve. This can be done through open-heart surgery or minimally invasive procedures.


What are the most common symptoms of a bicuspid valve?

Many people with bicuspid valves don’t experience any symptoms, but when symptoms do occur, they can include shortness of breath, chest pain or tightness, heart palpitations, fainting or lightheadedness, and difficulty exercising or doing physical activities.

What causes a bicuspid valve?

Bicuspid aortic valves are thought to be caused by genetic mutations or abnormalities. Some cases may also develop during fetal development.

How is a bicuspid valve diagnosed?

A bicuspid valve is usually diagnosed through an echocardiogram, but additional tests such as a cardiac MRI or CT scan may also be ordered.

When is treatment required for a bicuspid valve?

Treatment may be required if complications arise, such as aortic stenosis or regurgitation, or if the patient experiences symptoms such as chest pain, shortness of breath, or fainting.

What are the treatment options for a bicuspid valve?

Treatment options may include medications to manage symptoms, surgery to repair or replace the valve, or monitoring the valve through regular check-ups and tests.

Can a bicuspid valve be prevented?

Bicuspid aortic valves are a congenital condition, so they can’t be prevented. However, maintaining a healthy lifestyle and getting regular check-ups can help manage the condition and prevent complications.


  1. Bicuspid Aortic Valve. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/bicuspid-aortic-valve/symptoms-causes/syc-20351968#:~:text=Bicuspid%20aortic%20valve%20is%20a,normal%20three%20leaflets%20or%20cusps.
  2. Bicuspid Aortic Valve. American Heart Association. https://www.heart.org/-/media/files/health-topics/heart-valve-problems-and-disease/bicuspid-aortic-valve-ucm_450612.pdf
  3. Overview of Congenital Cardiovascular Anomalies. Merck Manual. https://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/overview-of-congenital-cardiovascular-anomalies

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